The study was conducted at the Peregrine Eye and Laser Institute in the Philippines. Patients were randomly assigned to one of two groups – manual CCI and femtosecond laser-assisted CCI. Wound sealability was measured based on the stability of the anterior chamber with a Seidal test.
Compared to the manual CCI group, incisions created with the femtosecond laser had significantly better wound sealability. More than two-thirds of eyes in the manual group (24 of 31 eyes, or 77.45%) required reformation of the anterior chamber and hydration of the wound compared to less than a quarter of the eyes in the femtosecond laser group (7 of 31 eyes, or 22.6%). In addition, only 9.7% of eyes in the manual group (3 of 31 eyes) maintained a formed anterior chamber compared to over half of the eyes in the femtosecond group (18 of 31, or 58.1%).
The researchers attributed the improved outcomes of the femtosecond laser to “more consistent, reproducible, and predictable wound geometry.”